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rabbit anti probdnf  (Abcam)

 
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    Abcam rabbit anti probdnf
    Rabbit Anti Probdnf, supplied by Abcam, used in various techniques. Bioz Stars score: 98/100, based on 2195 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti probdnf/product/Abcam
    Average 98 stars, based on 2195 article reviews
    rabbit anti probdnf - by Bioz Stars, 2026-03
    98/100 stars

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    Schematic diagram shows that peripheral inflammation upregulates proBDNF and p75 NTR in the spinal cord dorsal horn, which activate the downstream signaling ERK1/2 and NFκB, thereby promoting the spinal neuroinflammation and contributing to inflammatory pain. The administration of Ab-proB or p75 NTR -ECD ameliorates inflammatory pain by suppressing ERK1/2-NFκB pathway.

    Journal: Journal of Inflammation Research

    Article Title: Up-Regulation of ProBDNF/p75 NTR Signaling in Spinal Cord Drives Inflammatory Pain in Male Rats

    doi: 10.2147/JIR.S387127

    Figure Lengend Snippet: Schematic diagram shows that peripheral inflammation upregulates proBDNF and p75 NTR in the spinal cord dorsal horn, which activate the downstream signaling ERK1/2 and NFκB, thereby promoting the spinal neuroinflammation and contributing to inflammatory pain. The administration of Ab-proB or p75 NTR -ECD ameliorates inflammatory pain by suppressing ERK1/2-NFκB pathway.

    Article Snippet: Without washing, the sections were incubated with the primary antibodies (anti-proBDNF) as described previously, anti-p75NTR (catalog: #8238, rabbit monoclonal, 1:1000, Cell Signaling Technology), anti-GFAP (catalog: SAB5201104, mouse monoclonal, 1:1000, Millipore), anti-iba-1 (catalog: ab178846, rabbit monoclonal, 1:1000, Abcam), anti-iba-1 (catalog: ab178846, goat monoclonal, 1:500, Abcam), anti-NeuN (catalog: #94403, rabbit monoclonal, 1:1000, Cell Signaling Technology), anti-p-ERK (catalog: #4370, rabbit monoclonal, 1:1000, Cell Signaling Technology), anti-phospho-p65 (catalog: #3033, 1:1000, Cell Signaling Technology) overnight at 4 °C.

    Techniques: